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Breast cancer is the most common cancer among women worldwide, affecting millions of individuals each year. While breast cancer can occur in women of all ethnicities, research has shown that Ashkenazi Jewish women have a higher susceptibility to the disease compared to other populations. Understanding the factors contributing to this increased risk and the importance of genetic testing can empower individuals to take proactive steps in managing their health.
Background: Why Are Ashkenazi Jewish Women More Susceptible to Breast Cancer?
Ashkenazi Jews are individuals of Central and Eastern European Jewish descent with a distinct genetic heritage. Studies have indicated that Ashkenazi Jewish women have a higher prevalence of specific genetic mutations, particularly in the BRCA1 and BRCA2 genes, compared to the general population. These mutations significantly increase the risk of developing breast cancer, as well as ovarian and other cancers.
Geographical Distribution and Lifestyle Factors:
While Ashkenazi Jews are dispersed throughout the United States and other countries, there are significant populations in areas such as New York, New Jersey, and California. However, the increased risk of breast cancer among Ashkenazi Jewish women cannot be attributed solely to geographical location. Instead, genetic factors and cultural practices may play a more significant role.
Dietary Habits:
Some researchers have suggested that dietary habits among Ashkenazi Jews may contribute to their increased risk of breast cancer. Traditional Ashkenazi Jewish cuisine, which often includes foods high in fat and calories, may influence cancer risk. However, more research is needed to fully understand the impact of diet on breast cancer risk in this population.
Set Apart from Other Breast Cancer Statistics:
Ashkenazi Jewish women are set apart from other breast cancer statistical demographics due to their higher prevalence of genetic mutations associated with the disease. While genetic mutations such as BRCA1 and BRCA2 are found in all ethnic groups, they are particularly common among Ashkenazi Jews, affecting approximately 1 in 40 individuals compared to 1 in 400 in the general population [1]. This significantly elevates the lifetime risk of developing breast cancer and underscores the importance of genetic testing and early detection.
The Role of Genetic Testing:
Genetic testing plays a crucial role in identifying individuals at increased risk of hereditary breast cancer, including Ashkenazi Jewish women. Testing for mutations in the BRCA1 and BRCA2 genes can help assess an individual’s risk and inform personalized screening and prevention strategies.
Outcomes of Genetic Testing:
The outcomes of genetic testing for breast cancer risk can vary depending on the results. A positive result indicates the presence of a harmful mutation in the BRCA1 or BRCA2 gene, significantly increasing the lifetime risk of developing breast and ovarian cancers. In contrast, a negative result indicates the absence of these mutations, although it does not eliminate the possibility of developing breast cancer.
Ashkenazi Jewish women face a higher risk of breast cancer due to genetic factors, particularly mutations in the BRCA1 and BRCA2 genes. Genetic testing offers a valuable tool for identifying individuals at increased risk and guiding personalized screening and prevention strategies. By understanding their genetic risk factors and taking proactive measures, Ashkenazi Jewish women can empower themselves to make informed decisions about their health and well-being.
Genetic counseling and gene testing are part of Magnolia Breast Center’s comprehensive approach to breast health which encompasses all areas of this journey: prevention, diagnosis, treatment, and survivorship.
Magnolia Nurse practitioner Julie Stewart, MSN, APN, WHNP, is dedicated to evaluating women with risk factors for breast cancer and helps them develop a high risk screening program that works for them. Genetic counseling is completed in the office and if appropriate, genetic testing can be done at the same time.
Tam T. Mai, MD, FACS, FSSO
Board Certified Breast Surgical Oncologist
Dr. Tam T. Mai is a board-certified fellowship-trained breast surgeon certified by the American Board of Surgery and the Society of Surgical Oncology. She completed her oncoplastic breast surgery training at the University of Southern California, Hoag Breast Fellowship Program, under the world-renowned Dr. Melvin Silverstein, a pioneer of oncoplastic breast surgery. This approach utilizes plastic surgery techniques and principles to reshape the breast immediately following breast-conserving surgery for breast cancer to preserve the aesthetics of the breasts.
Before her move to Naples, Dr. Mai served as Medical Director of the Springfield Clinic Breast Health Center, an NAPBC-accredited multidisciplinary breast health center in central Illinois. During this time, she also participated in training the next generation of surgical residents in the General Surgery and Plastics Residency Programs at Southern Illinois University.
Dr. Mai is passionate about practicing evidence-based medicine and bringing high-level breast care to serve patients with breast diseases. She strongly believes in exercise as a treatment to improve overall wellness, breast cancer survival, and reduce the risk of cancer recurrence.
In her free time, Dr. Mai enjoys traveling, cooking, exercising, weight training, yoga, reading, and spending time with her family.
3530 Kraft Rd, Suite 202, Naples, FL 34105
239.758.PINK (7465)
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